Leukemia 2


Despite active research, to date no genetic aberration (inducing factor), shared by all patients, has been found in B-CLL. The monoclonality of B lymphocytes that develop in this disease implies that such a lesion existed in the cells initiating the clone. Although characteristic DNA abnormalities can occur later in the development of B-CLL clones, these are rarely found in the initial phases of the disease.

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